– SepaPrep™ UNI Series


NEW PRODUCT


SepaPrep™ UNI Series


Universal Reversed-Phase Performance for Routine and Method-Development Workflows


Series Overview


The SepaPrep™ UNI Series is designed as a robust, general-purpose reversed-phase solution for analytical and preparative HPLC applications. Built on high-purity spherical silica and optimized C18 surface bonding, UNI columns deliver stable retention, excellent peak shape, and reliable reproducibility for routine analysis and method development.


The balanced surface chemistry of the SepaPrep™ UNI Series provides predictable selectivity for non-polar to moderately polar compounds, while advanced end-capping minimizes secondary interactions. This design supports consistent performance across repeated injections, between column batches, and during scale-up from analytical to preparative formats.


Key Features



Optimized Endcapping for Improved Peak Shape: Minimizes residual silanol activity, delivering sharp and symmetrical peaks, including for basic analytes.

Enhanced Lot-to-Lot Reproducibility: Controlled silica selection and packing procedures ensure consistent chromatographic performance and reliable method transfer.

Versatile Reversed-Phase Selectivity: Balanced retention suitable for pharmaceuticals, natural products, and synthetic intermediates.



Silica Characteristics



















PhaseUSP CodeParticle SizePore SizeSpecific Surface AreaEndcappingCarbon LoadpH Range
C18L13 & 5 µm120 Å340 m2/gDouble14 %1.5 - 9.0


To maintain consistent performance and extend the working life of the column, it is recommended to operate the SepaPrep™ UNI C18 within its optimal pH range of 2.0 to 6.0. The maximum operating temperature is 60°C and the maximum pressure rating is 5,800 psi (40 MPa). For routine operation, pressure below 2,900 psi (20 MPa) is recommended.


Ordering Information









































































































































Column TypeID × LengthPhaseParticle SizePore DiameterPart Number
Analytical4.6 × 150 mmC183 µm120 ÅSH-200303-004X150
Analytical4.6 × 150 mmC185 µm120 ÅSH-200503-004X150
Analytical4.6 × 250 mmC183 µm120 ÅSH-200303-004X250
Analytical4.6 × 250 mmC185 µm120 ÅSH-200503-004X250
Preparative10 × 150 mmC185 µm120 ÅSH-200503-010X150
Preparative10 × 250 mmC185 µm120 ÅSH-200503-010X250
Preparative21.2 × 150 mmC185 µm120 ÅSH-200503-021X150
Preparative21.2 × 250 mmC185 µm120 ÅSH-200503-021X250
Preparative30 × 150 mmC185 µm120 ÅSH-200503-030X150
Preparative30 × 250 mmC185 µm120 ÅSH-200503-030X250
Preparative50 × 150 mmC185 µm120 ÅSH-200503-050X150
Preparative50 × 250 mmC185 µm120 ÅSH-200503-050X250
Guard4.6 × 10 mmC183 µm120 ÅSG-200303-004X10N (or D)
Guard4.6 × 10 mmC185 µm120 ÅSG-200503-004X10N (or D)
Guard10 × 10 mmC185 µm120 ÅSG-200503-010X10D
Guard21.2 × 10 mmC185 µm120 ÅSG-200503-021X10N